SCHEMBL13638336

SCHEMBL13638336

Cc1cc(C(=O)OC(=O)c2ccccc2)cc(C)c1OC(=O)c1c2ccccc2nc2ccc(O)cc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.39
MEN1 O00255 5/20 0.39
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 4/20 0.39
HPGD P15428 2/20 0.39
HSD17B10 Q99714 1/20 0.39
MAPT P10636 9/20 0.38
POLB P06746 7/20 0.38
GAA P10253 5/20 0.38
LMNA P02545 3/20 0.38
MAPK1 P28482 3/20 0.38
GFER P55789 2/20 0.38
RECQL P46063 1/20 0.38
HTT P42858 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
USP2 O75604 1/20 0.36
MCL1 Q07820 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12088076 0.90 MEN1 (0.48) KMT2AMEN1ALDH1A1KDM4EHPGD
SCHEMBL5663425 0.86 LMNA (0.44) KMT2AALDH1A1KDM4EHPGDMAPT
SCHEMBL3039691 0.84 KDM4E (0.47) KMT2AMEN1ALDH1A1KDM4EHPGD
SCHEMBL16141119 0.84 ALDH1A1 (0.39) KMT2AMEN1ALDH1A1KDM4EHPGD
SCHEMBL3092289 0.81 MEN1 (0.52) KMT2AMEN1ALDH1A1KDM4EHPGD
SCHEMBL13638337 0.81 MAPT (0.39) KMT2AMEN1ALDH1A1KDM4EHPGD
SCHEMBL12088154 0.80 MAPT (0.44) KMT2AALDH1A1KDM4EHPGDHSD17B10
SCHEMBL7050086 0.80 MEN1 (0.44) KMT2AMEN1ALDH1A1KDM4EHPGD
SCHEMBL13633651 0.79 UBE2N (0.36) KMT2AMEN1ALDH1A1KDM4EMAPT
SCHEMBL15413120 0.79 KMT2A (0.48) KMT2AMEN1ALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7611909-B1 Acridinium compound for use in the concurrent detection of target analytes in immunoassays or nucleic acid assays SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2009-11-03 US disclosed