Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | PKM | P14618 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4192297 | 0.90 | GAA (0.37) | MAPTGAALMNAPOLBKDM4E | |
| Bromide SCHEMBL4190244 | 0.89 | GAA (0.36) | MAPTGAALMNAPOLBKDM4E | |
| SCHEMBL13979971 | 0.87 | LMNA (0.43) | MAPTGAALMNAPOLBKDM4E | |
| SCHEMBL4194167 | 0.83 | KDM4E (0.32) | MAPTGAALMNAPOLBKDM4E | |
| SCHEMBL4178439 | 0.82 | MAPT (0.34) | MAPTGAALMNAPOLBKDM4E | |
| SCHEMBL12907529 | 0.82 | TTR (0.38) | MAPTGAALMNAPOLBKDM4E | |
| Bromide SCHEMBL8908965 | 0.81 | TTR (0.37) | MAPTGAALMNAPOLBKDM4E | |
| SCHEMBL17898189 | 0.81 | PPARA (0.45) | MAPTGAALMNAKDM4EHSD17B10 | |
| SCHEMBL13638336 | 0.81 | KMT2A (0.39) | MAPTGAALMNAPOLBKDM4E | |
| Trifluoroacetic Acid SCHEMBL4803136 | 0.81 | LMNA (0.37) | MAPTGAALMNAKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7611909-B1 | Acridinium compound for use in the concurrent detection of target analytes in immunoassays or nucleic acid assays | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2009-11-03 | — | — | US | disclosed |