Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 5/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12907529 | 0.88 | TTR (0.38) | PPARAACHELMNAMAPTCYP2C19 | |
| Bromide SCHEMBL8908965 | 0.87 | TTR (0.37) | PPARAACHELMNAMAPTCYP2C19 | |
| SCHEMBL6254465 | 0.84 | L3MBTL1 (0.42) | ACHEHPGDMAPTALDH1A1HTT | |
| SCHEMBL641602 | 0.83 | ACHE (0.32) | PPARAACHELMNAMAPTCYP2C19 | |
| SCHEMBL17898186 | 0.83 | PPARA (0.42) | PPARAACHEPPARGTSHRKIF11 | |
| SCHEMBL31163697 | 0.83 | ACHE (0.32) | PPARAACHELMNAMAPTCYP2C19 | |
| SCHEMBL3901332 | 0.82 | MAPT (0.36) | ACHELMNAMAPTALDH1A1HTT | |
| SCHEMBL13596778 | 0.82 | SPHK2 (0.36) | ACHETSHRMAPTALDH1A1KDM4E | |
| SCHEMBL4192297 | 0.81 | GAA (0.37) | ACHELMNAHPGDMAPTCYP2C19 | |
| Bromide SCHEMBL7596648 | 0.81 | SPHK2 (0.36) | ACHETSHRMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160195524-A1 | Automated Assay | THE UNIVERSITY OF STRATHCLYDE (GB) | 2016-07-07 | — | — | US | disclosed |