Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.46 |
| ▸ | PIM1 | P11309 | 4/20 | 0.45 |
| ▸ | GPR6 | P46095 | 2/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 3/20 | 0.37 |
| ▸ | PAICS | P22234 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.35 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634792 | 1.00 | PDE10A (0.46) | PDE10APIM1GPR6IRAK4NAMPT | |
| SCHEMBL13634502 | 0.88 | GPR6 (0.44) | PDE10AGPR6IRAK4NAMPTPAICS | |
| SCHEMBL13634821 | 0.88 | GPR6 (0.44) | PDE10AGPR6IRAK4NAMPTPAICS | |
| SCHEMBL13634500 | 0.85 | GPR6 (0.42) | PDE10APIM1GPR6PAICSSMO | |
| SCHEMBL13634835 | 0.84 | PIM1 (0.42) | PIM1GPR6PAICS | |
| SCHEMBL13638762 | 0.84 | PDE10A (0.40) | PDE10APIM1GPR6NAMPTPAICS | |
| SCHEMBL13634790 | 0.83 | PIM1 (0.41) | PDE10APIM1GPR6PAICSPIM3 | |
| SCHEMBL13634623 | 0.83 | PIM1 (0.44) | PDE10APIM1GPR6IRAK4NAMPT | |
| SCHEMBL13634798 | 0.83 | PIM1 (0.48) | PIM1GPR6IRAK4PAICSPIM3 | |
| SCHEMBL13634601 | 0.83 | MCHR1 (0.43) | GPR6IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |