Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162577 | 0.89 | LDHA (0.36) | HCRTR1HCRTR2ADORA2AADORA1FFAR1 | |
| SCHEMBL13634283 | 0.82 | ADORA2A (0.35) | HRH3ADORA2AADORA1MEN1KMT2A | |
| SCHEMBL3541650 | 0.76 | RAB9A (0.45) | MEN1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL15888542 | 0.75 | GAA (0.47) | MEN1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL13161921 | 0.73 | HRH3 (0.60) | HRH3HCRTR1HCRTR2CRBNMEN1 | |
| SCHEMBL2552182 | 0.72 | HRH3 (0.45) | HRH3HCRTR1HCRTR2CRBNADORA2A | |
| SCHEMBL3559561 | 0.72 | PTGER1 (0.38) | GAASMN1; SMN2ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL13634222 | 0.71 | PTGER1 (0.38) | GAASMN1; SMN2ALDH1A1POLBL3MBTL1 | |
| SCHEMBL13163985 | 0.71 | HRH3 (0.49) | HRH3HCRTR1HCRTR2CRBNMAOA | |
| SCHEMBL15888628 | 0.70 | GAA (0.43) | MEN1KMT2AMAPTGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |