Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.30 |
| ▸ | CFB | P00751 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162577 | 0.83 | LDHA (0.36) | ADORA2AADORA1FFAR1SMN1; SMN2 | |
| SCHEMBL13638866 | 0.82 | HRH3 (0.41) | ADORA2AADORA1HRH3L3MBTL1MEN1 | |
| SCHEMBL13634185 | 0.68 | HRH3 (0.50) | HRH3L3MBTL1MEN1SMN1; SMN2NPC1 | |
| SCHEMBL3559247 | 0.67 | HRH3 (0.55) | HRH3L3MBTL1MEN1SMN1; SMN2NPC1 | |
| SCHEMBL3541650 | 0.66 | RAB9A (0.45) | MEN1KMT2ASMN1; SMN2NPC1POLB | |
| SCHEMBL10278217 | 0.66 | HRH3 (0.48) | HRH3L3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13634335 | 0.66 | PDE10A (0.35) | DPP4 | |
| SCHEMBL15888542 | 0.65 | GAA (0.47) | L3MBTL1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL3545517 | 0.65 | PDK1 (0.39) | ADORA2AADORA1L3MBTL1MEN1KMT2A | |
| SCHEMBL3559561 | 0.63 | PTGER1 (0.38) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |