Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 9/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 8/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3559561 | 0.86 | PTGER1 (0.38) | PTGER1KDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL15888542 | 0.83 | GAA (0.47) | ALDH1A1GAASMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL13162577 | 0.81 | LDHA (0.36) | PTGER1KDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL13634335 | 0.78 | PDE10A (0.35) | PDE10A | |
| SCHEMBL13270380 | 0.74 | LDHA (0.47) | PTGER1KDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL3549852 | 0.73 | FPR2 (0.40) | PTGER1KDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL13638848 | 0.73 | PDE10A (0.32) | PDE10A | |
| SCHEMBL13634291 | 0.72 | LDHA (0.36) | PTGER1KDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL3550523 | 0.71 | PTGER1 (0.46) | PTGER1KDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL13638866 | 0.71 | HRH3 (0.41) | ALDH1A1GAASMN1; SMN2POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206707-B1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2014-07-23 | — | — | EP | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |