Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638971 | 0.86 | SIGMAR1 (0.43) | ADORA2AADORA1SIGMAR1 | |
| SCHEMBL13638857 | 0.77 | ALDH1A1 (0.47) | ACHE | |
| SCHEMBL13638752 | 0.75 | GRM2 (0.43) | MCHR1 | |
| SCHEMBL20961917 | 0.74 | ALDH1A1 (0.40) | — | |
| SCHEMBL13638957 | 0.73 | HRH3 (0.49) | — | |
| SCHEMBL13638859 | 0.72 | HDAC8 (0.51) | HDAC1HDAC6ACHE | |
| SCHEMBL13638843 | 0.69 | CCNC (0.37) | — | |
| SCHEMBL13638739 | 0.69 | GRM2 (0.42) | — | |
| SCHEMBL13638876 | 0.68 | DRD4 (0.49) | SIGMAR1 | |
| SCHEMBL13638875 | 0.68 | HRH3 (0.42) | HDAC6ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |