Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 7/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638875 | 0.75 | HRH3 (0.42) | BCHEACHEMAPT | |
| SCHEMBL20961917 | 0.72 | ALDH1A1 (0.40) | LMNAMAPT | |
| SCHEMBL13638747 | 0.68 | HRH3 (0.40) | PARP1LTA4HLMNA | |
| SCHEMBL12969186 | 0.68 | GRM2 (0.41) | GRM2PARP1LTA4HBRAFMAOB | |
| SCHEMBL14614616 | 0.67 | PYCR1 (0.56) | BCHEACHE | |
| SCHEMBL12474 | 0.67 | PYCR1 (0.50) | PARP1LTA4HBRAFACHEMAOB | |
| SCHEMBL26012094 | 0.66 | LTA4H (0.45) | GRM2PARP1BCHELTA4HBRAF | |
| SCHEMBL3151763 | 0.66 | LTA4H (0.47) | GRM2PARP1LTA4HBRAFMAPT | |
| SCHEMBL1239426 | 0.66 | KDM4E (0.59) | PARP1LTA4HBRAFLMNAMAOB | |
| SCHEMBL8381376 | 0.66 | ERN1 (0.58) | LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |