Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 19/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638752 | 0.83 | GRM2 (0.43) | DRD4GRM2 | |
| SCHEMBL13638970 | 0.82 | SYK (0.37) | DRD4GRM2 | |
| SCHEMBL13638957 | 0.76 | HRH3 (0.49) | — | |
| SCHEMBL1927637 | 0.74 | DRD4 (0.63) | DRD4DRD2 | |
| SCHEMBL9582407 | 0.74 | DRD4 (0.73) | DRD4DRD2 | |
| SCHEMBL1317540 | 0.74 | DRD4 (0.73) | DRD4DRD2 | |
| SCHEMBL9582052 | 0.74 | DRD4 (0.73) | DRD4DRD2 | |
| SCHEMBL13638859 | 0.74 | HDAC8 (0.51) | — | |
| SCHEMBL13162596 | 0.72 | DRD4 (0.50) | DRD4GRM2DRD2SIGMAR1 | |
| SCHEMBL13638973 | 0.72 | GRM2 (0.49) | DRD4GRM2DRD2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |