Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | VEGFA | P15692 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.36 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.36 |
| ▸ | PNP | P00491 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13270278 | 0.81 | HDAC8 (0.49) | HDAC8HDAC6HDAC1MAPK1VEGFA | |
| SCHEMBL13638876 | 0.74 | DRD4 (0.49) | — | |
| SCHEMBL13479179 | 0.73 | HDAC8 (0.64) | HDAC8HDAC6HDAC1MAPK1VEGFA | |
| SCHEMBL13638748 | 0.72 | ADORA2A (0.35) | HDAC6HDAC1ACHE | |
| SCHEMBL13638863 | 0.72 | HDAC8 (0.54) | HDAC8HDAC6HDAC1MAPK1VEGFA | |
| SCHEMBL3569375 | 0.72 | HDAC8 (0.63) | HDAC8HDAC6HDAC1MAPK1VEGFA | |
| SCHEMBL13638971 | 0.72 | SIGMAR1 (0.43) | ALDH1A1 | |
| SCHEMBL12642706 | 0.72 | HDAC8 (0.67) | HDAC8HDAC6HDAC1MAPK1VEGFA | |
| SCHEMBL1241170 | 0.72 | HDAC8 (0.67) | HDAC8HDAC6HDAC1MAPK1VEGFA | |
| SCHEMBL3565573 | 0.72 | HDAC8 (0.63) | HDAC8HDAC6HDAC1MAPK1VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |