Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638959 | 0.88 | SIGMAR1 (0.52) | HRH3ERN1KCNJ1 | |
| SCHEMBL19603341 | 0.81 | ERN1 (0.51) | HRH3ERN1NCF1SMN1; SMN2HTT | |
| SCHEMBL13638752 | 0.81 | GRM2 (0.43) | — | |
| SCHEMBL13638857 | 0.81 | ALDH1A1 (0.47) | HRH3NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL13638739 | 0.80 | GRM2 (0.42) | ERN1NCF1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL23926365 | 0.78 | PIK3CD (0.58) | HRH3ERN1NCF1SMN1; SMN2HTT | |
| SCHEMBL16243189 | 0.78 | HTT (0.65) | SMN1; SMN2HTTNPC1TP53TSHR | |
| SCHEMBL6223785 | 0.77 | HRH3 (0.53) | HRH3ERN1NCF1SMN1; SMN2HTT | |
| SCHEMBL13638876 | 0.76 | DRD4 (0.49) | — | |
| SCHEMBL13638971 | 0.75 | SIGMAR1 (0.43) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |