Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 5/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 7/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CCL2 | P13500 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638801 | 0.84 | GRM2 (0.46) | GRM2KCNH2CNR2CNR1CCNC | |
| SCHEMBL13638876 | 0.83 | DRD4 (0.49) | GRM2DRD4 | |
| SCHEMBL13638957 | 0.81 | HRH3 (0.49) | — | |
| SCHEMBL13638748 | 0.75 | ADORA2A (0.35) | MCHR1 | |
| SCHEMBL8291021 | 0.74 | DRD4 (0.57) | GRM2CNR2CNR1DRD4 | |
| SCHEMBL13638857 | 0.74 | ALDH1A1 (0.47) | GRM2DRD4 | |
| Ammonia Solution, Strong SCHEMBL4483710 | 0.73 | DRD4 (0.56) | GRM2CNR2CNR1DRD4 | |
| SCHEMBL13638959 | 0.73 | SIGMAR1 (0.52) | KCNH2 | |
| SCHEMBL12375 | 0.72 | ALDH1A1 (0.49) | CNR2CNR1DRD4KDM1A | |
| Ammonia Solution, Strong SCHEMBL2849850 | 0.72 | DRD4 (0.57) | GRM2KCNH2CNR2CNR1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |