Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 12/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | CSF1R | P07333 | 2/20 | 0.49 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162040 | 0.90 | BRAF (0.54) | BRAFCYP11B2CSF1RKITKDR | |
| SCHEMBL13163949 | 0.78 | CCNE2 (0.49) | CYP11B2NAMPTPOLBMAPTTDP1 | |
| SCHEMBL13638807 | 0.77 | ALDH1A1 (0.47) | CYP11B2NAMPTPOLBMAPTTDP1 | |
| SCHEMBL13634247 | 0.77 | SMN1; SMN2 (0.48) | CYP11B2NAMPTPOLBMAPTTRPV1 | |
| SCHEMBL13162750 | 0.75 | SMN1; SMN2 (0.46) | CYP11B2POLBMAPTTDP1NPC1 | |
| SCHEMBL13162877 | 0.75 | MAPT (0.62) | BRAFCYP11B2CSF1RKITKDR | |
| SCHEMBL3934041 | 0.74 | BRAF (0.63) | BRAFCYP11B2CSF1RKITKDR | |
| SCHEMBL13161982 | 0.74 | BRAF (0.74) | BRAFCYP11B2CSF1RKITKDR | |
| SCHEMBL3943800 | 0.73 | BRAF (0.80) | BRAFCYP11B2CSF1RNAMPT | |
| SCHEMBL13162883 | 0.73 | ABL1 (0.56) | BRAFCYP11B2POLBMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |