Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162750 | 0.91 | SMN1; SMN2 (0.46) | SMN1; SMN2POLBALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL13638900 | 0.77 | BRAF (0.54) | TRPV1POLBCYP11B2NAMPTMAPT | |
| SCHEMBL13163949 | 0.77 | CCNE2 (0.49) | SMN1; SMN2TRPV1POLBALDH1A1CYP11B1 | |
| SCHEMBL13161892 | 0.77 | SMN1; SMN2 (0.56) | SMN1; SMN2POLBALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL13163901 | 0.76 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1CYP11B1CYP11B2KMT2A | |
| SCHEMBL13634152 | 0.76 | SIRT6 (0.51) | SMN1; SMN2ALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL13162040 | 0.75 | BRAF (0.54) | SMN1; SMN2POLBALDH1A1CYP11B2NAMPT | |
| SCHEMBL13163083 | 0.75 | MAPT (0.60) | SMN1; SMN2POLBALDH1A1KMT2AMAPT | |
| SCHEMBL13162752 | 0.74 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL13634274 | 0.73 | ALDH1A1 (0.50) | POLBALDH1A1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |