Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162040 | 0.87 | BRAF (0.54) | ALDH1A1HPGDTDP1SMN1; SMN2KDM4E | |
| SCHEMBL13163949 | 0.86 | CCNE2 (0.49) | ALDH1A1HPGDTDP1SMN1; SMN2KDM4E | |
| SCHEMBL13162750 | 0.83 | SMN1; SMN2 (0.46) | ALDH1A1HPGDTDP1SMN1; SMN2KDM4E | |
| SCHEMBL13638804 | 0.77 | RAB9A (0.62) | ALDH1A1TDP1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL13638900 | 0.77 | BRAF (0.54) | TDP1NPC1MAPTTRPV1POLB | |
| SCHEMBL13634247 | 0.73 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2MAPTTRPV1HIF1A | |
| SCHEMBL13638862 | 0.73 | NTRK1 (0.39) | NPC1RAB9A | |
| SCHEMBL13638854 | 0.71 | RAB9A (0.62) | ALDH1A1TDP1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL13638956 | 0.71 | CYP11B2 (0.62) | ALDH1A1HPGDKDM4ELRRK2HIF1A | |
| SCHEMBL13638850 | 0.69 | KMT2A (0.42) | ALDH1A1TRPV1LRRK2NAMPTCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |