Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 10/20 | 0.43 |
| ▸ | BCHE | P06276 | 8/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12868991 | 0.84 | FFAR1 (0.51) | ACHEBCHEFFAR1L3MBTL1 | |
| SCHEMBL765724 | 0.79 | BCHE (0.51) | ACHEBCHEFFAR1L3MBTL1TYR | |
| SCHEMBL10206356 | 0.78 | HTT (0.46) | ACHEBCHEL3MBTL1 | |
| SCHEMBL765839 | 0.78 | HTT (0.41) | ACHEBCHEL3MBTL1 | |
| SCHEMBL765840 | 0.77 | ALDH1A1 (0.42) | ACHEBCHEL3MBTL1GAA | |
| SCHEMBL20738296 | 0.77 | BCHE (0.53) | ACHEBCHETYR | |
| SCHEMBL13094090 | 0.76 | ACHE (0.41) | ACHEBCHE | |
| SCHEMBL20206848 | 0.76 | ACHE (0.41) | ACHEBCHEL3MBTL1GAA | |
| SCHEMBL765878 | 0.76 | HTT (0.42) | ACHEBCHEL3MBTL1GAA | |
| SCHEMBL20374238 | 0.76 | DUT (0.42) | ACHEBCHEL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304403-B2 | Heterocyclic CETP inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-11-06 | — | — | US | disclosed |