Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | NAPEPLD | Q6IQ20 | 2/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.33 |
| ▸ | SCD | O00767 | 2/20 | 0.33 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.33 |
| ▸ | ITK | Q08881 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634908 | 0.95 | HDAC1 (0.37) | HDAC1WDR5ENPP2KMT2ANAPEPLD | |
| SCHEMBL13634647 | 0.93 | HDAC1 (0.36) | HDAC1WDR5ENPP2KMT2ANAPEPLD | |
| SCHEMBL13634852 | 0.93 | HDAC1 (0.36) | HDAC1WDR5ENPP2KMT2ANAPEPLD | |
| SCHEMBL13270788 | 0.87 | WDR5 (0.34) | HDAC1WDR5ENPP2NAPEPLDSCD | |
| SCHEMBL13638780 | 0.87 | PDCD1 (0.36) | KMT2AOPRK1IRAK4SCDSCD5 | |
| SCHEMBL13639003 | 0.86 | PIN1 (0.37) | KMT2AOPRK1NAPEPLDSCDSCD5 | |
| SCHEMBL2770606 | 0.85 | PIN1 (0.37) | KMT2AOPRK1NAPEPLDSCDSCD5 | |
| SCHEMBL2770504 | 0.85 | PIN1 (0.37) | KMT2AOPRK1NAPEPLDSCDSCD5 | |
| SCHEMBL2770059 | 0.85 | NAPEPLD (0.40) | NAPEPLDSCDSCD5 | |
| SCHEMBL13638912 | 0.85 | KMT2A (0.47) | KMT2AOPRK1IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |