Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14464212 | 0.81 | PTGER3 (0.47) | — | |
| SCHEMBL12299096 | 0.73 | PTGER2 (0.39) | MMP1MMP2MMP9MMP13 | |
| SCHEMBL12330063 | 0.72 | PTGER4 (0.40) | MMP1MMP2MMP9MMP13 | |
| SCHEMBL3550329 | 0.71 | L3MBTL1 (0.61) | SMN1; SMN2ALDH1A1KDM4EGAA | |
| SCHEMBL1807775 | 0.70 | HRH3 (0.59) | MMP1MMP2MMP9MMP13KMT2A | |
| SCHEMBL12298922 | 0.69 | PTGER3 (0.40) | POLBMMP1MMP2MMP9MMP13 | |
| SCHEMBL2215321 | 0.69 | HRH3 (0.61) | POLBMMP1MMP2MMP9MMP13 | |
| SCHEMBL14199640 | 0.69 | ALDH1A1 (0.51) | POLBKDM4CTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL2142883 | 0.69 | MMP1 (0.50) | MMP1MMP2MMP9MMP13ALDH1A1 | |
| SCHEMBL28785165 | 0.69 | MMP13 (0.54) | MMP1MMP2MMP9MMP13ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481976-B1 | 8-AZAPROSTAGLANDIN DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2012-11-07 | — | — | EP | disclosed |