Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.30 |
| ▸ | HTR3B | O95264 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.30 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15304198 | 0.80 | ACHE (0.43) | SNCAKDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL5892425 | 0.78 | ALDH1A1 (0.39) | SNCAKDM4EALDH1A1HTR3EHTR3B | |
| SCHEMBL10290477 | 0.77 | ALDH1A1 (0.31) | ALDH1A1HTT | |
| SCHEMBL2723790 | 0.77 | TDP1 (0.49) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL17940744 | 0.74 | CA1 (0.40) | SNCAMAPTALDH1A1HTT | |
| SCHEMBL7163811 | 0.72 | NPC1 (0.34) | SNCAKDM4EALDH1A1HTT | |
| SCHEMBL10258968 | 0.71 | TNKS2 (0.40) | KDM4E | |
| SCHEMBL15304200 | 0.71 | ACHE (0.43) | SNCAKDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL15976369 | 0.70 | DRD2 (0.41) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL14261558 | 0.70 | IDO1 (0.45) | SNCAKDM4EMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1995242-B1 | NOVEL 1,2,3,4-TETRAHYDROQUINOXALINE DERIVATIVE HAVING GLUCOCORTICOID RECEPTOR BINDING ACTIVITY | SANTEN PHARMACEUTICAL CO LTD (JP) | 2012-11-07 | — | — | EP | disclosed |