Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18933773 | 0.80 | CASP1 (0.35) | — | |
| SCHEMBL615942 | 0.78 | ALDH1A1 (0.38) | ALDH1A1HTT | |
| SCHEMBL13639298 | 0.77 | SNCA (0.33) | ALDH1A1HTT | |
| SCHEMBL613715 | 0.75 | CYP3A4 (0.47) | ALDH1A1HTT | |
| SCHEMBL614874 | 0.73 | KDM4E (0.37) | ALDH1A1 | |
| SCHEMBL2920762 | 0.73 | CYP3A4 (0.32) | — | |
| SCHEMBL16974592 | 0.70 | ALDH1A1 (0.39) | ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL16974558 | 0.69 | ALDH1A1 (0.38) | ALDH1A1HTT | |
| SCHEMBL10206836 | 0.67 | TDP1 (0.43) | ALDH1A1HTT | |
| SCHEMBL1066081 | 0.66 | CYP3A4 (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120309960-A1 | MACROCYCLES AS FACTOR XIA INHIBITORS | BRISTOL-MEYERS SQUIBB COMPANY | 2012-12-06 | — | — | US | disclosed |
| US-20120041190-A1 | MACROCYCLES AS FACTOR XIA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041190-A1 | MACROCYCLES AS FACTOR XIA INHIBITORS | TFPI, TFPI2, F11 | ALDH1A1 4598/4885HTT 2077/4885 |
| US-20120309960-A1 | MACROCYCLES AS FACTOR XIA INHIBITORS | TFPI, TFPI2, F11 | ALDH1A1 4598/4885HTT 2077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.