Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PAM | P19021 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL233451 | 0.81 | HTT (0.39) | ALDH1A1HTTPOLBSMN1; SMN2NAAA | |
| SCHEMBL13291851 | 0.77 | ALDH1A1 (0.68) | MGLLALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL9798558 | 0.76 | NAAA (0.32) | HTTNAAA | |
| SCHEMBL11697916 | 0.75 | ALDH1A1 (0.50) | MGLLALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL4911689 | 0.75 | ALDH1A1 (0.66) | MGLLALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL4570308 | 0.73 | ALDH1A1 (0.68) | MGLLALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL231863 | 0.73 | TSHR (0.49) | ALDH1A1NAAA | |
| Methacrylic Acid SCHEMBL31166304 | 0.72 | ALDH1A1 (0.33) | ALDH1A1HTTPOLBNAAA | |
| SCHEMBL16465101 | 0.72 | CYP3A4 (0.49) | ALDH1A1HTTPOLBSMN1; SMN2MEN1 | |
| SCHEMBL16464737 | 0.72 | LMNA (0.46) | ALDH1A1HTTPOLBSMN1; SMN2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692126-B1 | REACTIVE CYCLIC CARBONATES AND UREAS USED FOR MODIFYING BIOMOLECULES, POLYMERS, AND SURFACES | HENKEL AG & CO KGAA (DE) | 2012-11-07 | — | — | EP | disclosed |