SCHEMBL233451

SCHEMBL233451

O=C(OCCCCC1COC(=O)O1)Oc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.39
TDP1 Q9NUW8 1/20 0.34
MMP2 P08253 2/20 0.33
MMP9 P14780 2/20 0.33
MMP12 P39900 2/20 0.33
ALDH1A1 P00352 2/20 0.33
NAAA Q02083 1/20 0.33
ASAH1 Q13510 1/20 0.33
MMP1 P03956 1/20 0.33
POLB P06746 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALOX5 P09917 2/20 0.32
HTR1A P08908 1/20 0.32
ADRA1D P25100 1/20 0.32
ADRA1A P35348 1/20 0.32
ADRA1B P35368 1/20 0.32
PPARG P37231 1/20 0.32
PPARD Q03181 1/20 0.32
MTNR1A P48039 1/20 0.32
ALOX12 P18054 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL230593 0.83 L3MBTL1 (0.41) HTTTDP1ALOX5
SCHEMBL13639780 0.81 MGLL (0.47) HTTALDH1A1NAAAPOLBSMN1; SMN2
SCHEMBL9798558 0.76 NAAA (0.32) HTTNAAA
SCHEMBL13217150 0.75 MIF (0.47) HTTALDH1A1POLBALOX5RAB9A
SCHEMBL16814873 0.75 TDP1 (0.52) TDP1ALDH1A1
SCHEMBL9798283 0.74 TSHR (0.44) ALDH1A1
SCHEMBL231863 0.73 TSHR (0.49) ALDH1A1NAAA
Methacrylic Acid SCHEMBL31166304 0.72 ALDH1A1 (0.33) HTTTDP1ALDH1A1NAAAPOLB
SCHEMBL229724 0.72 TSHR (0.45) HTTTDP1ALDH1A1NAAAPOLB
SCHEMBL9999670 0.72 CYP1A2 (0.37) HTTALDH1A1SMN1; SMN2PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8324145-B2 Anti-grey detergent comprising a cyclic carbonate or urea HENKEL AG & CO. KGAA (DE) 2012-12-04 US claimed
US-8318649-B2 Cleaning agents comprising a cyclic carbonate Henkel, AG & Co. KGAA (DE) 2012-11-27 US claimed
EP-1692126-B1 REACTIVE CYCLIC CARBONATES AND UREAS USED FOR MODIFYING BIOMOLECULES, POLYMERS, AND SURFACES HENKEL AG & CO KGAA (DE) 2012-11-07 EP claimed
EP-2129763-B1 PRODUCT FOR TREATING HARD SURFACES HENKEL AG & CO KGAA (DE) 2012-08-08 EP claimed
US-20120006358-A1 CLEANING AGENTS HENKEL AG & CO. KGAA (DE) 2012-01-12 US claimed
US-20120004155-A1 ANTI-GREY DETERGENT HENKEL AG & CO. KGAA (DE) 2012-01-05 US claimed
US-7728069-B2 Reactive cyclic carbonates and ureas used for modifying biomolecules, polymers, and surfaces HENKEL AG & CO. KGAA (DE) 2010-06-01 US claimed
US-20100041574-A1 PRODUCT FOR TREATING HARD SURFACES HENKEL AG & CO. KGAA (DE) 2010-02-18 US claimed
WO-2008119830-A2 FIXATING FRAGRANCES ORIGINATING FROM DETERGENTS AND CLEANING AGENTS ON HARD AND SOFT SURFACES HENKEL AG & CO. KGAA (DE) 2008-10-09 WO claimed
US-20070092656-A1 Reactive cyclic carbonates and ureas used for modifying biomolecules, polymers, and surfaces DEUTSCHES WOLLFORSCHUNGSINSTITUT AN DER RWTH AACHEN E.V. (DE) 2007-04-26 US claimed
EP-1692126-A1 REACTIVE CYCLIC CARBONATES AND UREAS USED FOR MODIFYING BIOMOLECULES, POLYMERS, AND SURFACES Deutsches Wollforschungsinstitut an der Rheinisch-Westfälischen Technischen Hochschule Aachen e.V. (DE) 2006-08-23 EP claimed
WO-2005058863-A1 REACTIVE CYCLIC CARBONATES AND UREAS USED FOR MODIFYING BIOMOLECULES, POLYMERS, AND SURFACES DEUTSCHES WOLLFORSCHUNGSINSTITUT AN DER RWTH AACHEN E.V. (DE) 2005-06-30 WO claimed
EP-2134826-B1 ANTI-GREY DETERGENT HENKEL AG & CO KGAA (DE) 2015-11-04 EP disclosed
EP-2487231-B1 Agent for treating hard surfaces HENKEL AG & CO KGAA (DE) 2015-08-05 EP disclosed
EP-2487230-B1 Colour-safe cleaning or washing agent HENKEL AG & CO KGAA (DE) 2014-12-03 EP disclosed
US-8524648-B2 Color-protecting detergents or cleaning agents HENKEL AG & CO. KGAA (DE) 2013-09-03 US disclosed
WO-2008119836-A2 DETERGENT CONTAINING SOIL-RELEASING SUBSTANCES HENKEL AG & CO. KGAA (DE) 2008-10-09 WO disclosed
WO-2008119830-A2 FIXATING FRAGRANCES ORIGINATING FROM DETERGENTS AND CLEANING AGENTS ON HARD AND SOFT SURFACES HENKEL AG & CO. KGAA (DE) 2008-10-09 WO disclosed
US-20070092656-A1 Reactive cyclic carbonates and ureas used for modifying biomolecules, polymers, and surfaces DEUTSCHES WOLLFORSCHUNGSINSTITUT AN DER RWTH AACHEN E.V. (DE) 2007-04-26 US disclosed
US-20070092656-A1 Reactive cyclic carbonates and ureas used for modifying biomolecules, polymers, and surfaces DEUTSCHES WOLLFORSCHUNGSINSTITUT AN DER RWTH AACHEN E.V. (DE) 2007-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120006358-A1 CLEANING AGENTS PUF60, PCNA, PKD1 HTT 3174/4885TDP1 1364/4885MMP2 2242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.