Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13640224 | 0.81 | GAA (0.46) | CA1CA2GABRA1GABRB1GABRB2 | |
| SCHEMBL544651 | 0.79 | CA1 (0.67) | CA1CA2GABRA1GABRB1GABRB2 | |
| SCHEMBL27658629 | 0.77 | KDM4E (0.47) | CA1CA2GABRA1GABRB1GABRB2 | |
| Benzene SCHEMBL9247233 | 0.76 | BCL2 (0.46) | CA1CA2GABRA1GABRB1LMNA | |
| SCHEMBL19439615 | 0.74 | CA1 (0.48) | CA1CA2GABRA1GABRB1GABRB2 | |
| SCHEMBL13640243 | 0.73 | PKM (0.42) | CA1CA2GABRA1GABRB1GABRB2 | |
| SCHEMBL4402447 | 0.73 | CA1 (0.52) | CA1CA2GABRA1GABRB1GABRB2 | |
| SCHEMBL7942520 | 0.73 | GABRA1 (0.61) | CA1CA2GABRA1GABRB1GABRB2 | |
| SCHEMBL4612220 | 0.73 | CA1 (0.52) | CA1CA2GABRA1GABRB1GABRB2 | |
| SCHEMBL12352193 | 0.73 | CA1 (0.58) | CA1CA2GABRA1GABRB1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120283335-A1 | Analogs of Propofol, Preparation Thereof and Use as Anesthetics | SIGNATURE THERAPEUTICS, INC. | 2012-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283335-A1 | Analogs of Propofol, Preparation Thereof and Use as Anesthetics | GABRP, CYP4F11, CYP2F1 | CA1 2438/4885CA2 2706/4885GABRA1 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.