Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 7/20 | 0.54 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13641657 | 1.00 | VDR (0.54) | VDRCYP24A1 | |
| SCHEMBL13158137 | 1.00 | VDR (0.54) | VDRCYP24A1 | |
| SCHEMBL12634985 | 1.00 | VDR (0.54) | VDRCYP24A1 | |
| SCHEMBL13839178 | 1.00 | VDR (0.54) | VDRCYP24A1 | |
| SCHEMBL9010622 | 0.91 | VDR (0.56) | VDRCYP24A1 | |
| SCHEMBL14357531 | 0.91 | VDR (0.56) | VDRCYP24A1 | |
| SCHEMBL9010530 | 0.90 | VDR (0.60) | VDRCYP24A1 | |
| SCHEMBL9010583 | 0.89 | VDR (0.57) | VDRCYP24A1 | |
| SCHEMBL9883792 | 0.89 | VDR (0.54) | VDRCYP24A1 | |
| SCHEMBL14409184 | 0.89 | VDR (0.54) | VDRCYP24A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120283228-A1 | 2alpha-Methyl and 2beta-Methyl Analogs of 19,26-Dinor-1alpha,25-Dihydroxyvitamin D3 and Their Uses | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-11-08 | — | — | US | disclosed |
| US-20090170820-A1 | 2-Methylene-(20S,25R)-19,26-Dinor-Vitamin D Analogs | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170820-A1 | 2-Methylene-(20S,25R)-19,26-Dinor-Vitamin D Analogs | CYP24A1, VDR, CYP27B1 | VDR 2/4885CYP24A1 1/4885 |
| US-20120283228-A1 | 2alpha-Methyl and 2beta-Methyl Analogs of 19,26-Dinor-1alpha,25-Dihydroxyvitamin D3 and Their Uses | CYP24A1, VDR, CYP27B1 | VDR 2/4885CYP24A1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.