Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.64 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.61 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 3/20 | 0.58 |
| ▸ | PPARA | Q07869 | 3/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.57 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.57 |
| ▸ | ITGAV | P06756 | 1/20 | 0.57 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.57 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.57 |
| ▸ | MMP12 | P39900 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 2/20 | 0.55 |
| ▸ | PPARD | Q03181 | 1/20 | 0.55 |
| ▸ | LAP3 | P28838 | 1/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.54 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13643129 | 0.87 | MAOB (0.65) | MAOBFFAR1FFAR4PPARGPPARA | |
| SCHEMBL758429 | 0.86 | CYSLTR2 (0.67) | MAOBFFAR1FFAR4PPARGPPARA | |
| SCHEMBL14542152 | 0.84 | CPA1 (0.60) | ITGB3ITGB1ITGAVITGB5ITGB6 | |
| SCHEMBL750878 | 0.84 | CPA1 (0.60) | ITGB3ITGB1ITGAVITGB5ITGB6 | |
| SCHEMBL16488807 | 0.84 | CPA1 (0.60) | ITGB3ITGB1ITGAVITGB5ITGB6 | |
| SCHEMBL357349 | 0.83 | MAOB (0.57) | MAOBFFAR1FFAR4PPARGPPARA | |
| SCHEMBL360368 | 0.83 | MAOB (0.57) | MAOBFFAR1FFAR4PPARGPPARA | |
| SCHEMBL289033 | 0.82 | LTA4H (0.67) | MAOBFFAR1FFAR4PPARGPPARA | |
| SCHEMBL5888154 | 0.82 | LTA4H (0.67) | MAOBFFAR1FFAR4PPARGPPARA | |
| SCHEMBL9863278 | 0.82 | CPA1 (0.58) | ITGB3ITGB1ITGAVITGB5ITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8772507-B2 | Imidazole-benzamide anti-cancer agents | CYTOKINETICS, INC. (US) | 2014-07-08 | — | — | US | disclosed |
| US-20130096315-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | QIAN XIANGPING (US) | 2013-04-18 | — | — | US | disclosed |
| US-20120283287-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | QIAN XIANGPING (US) | 2012-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283287-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | KIF5B, KIF2C, PLK1 | MAOB 3045/4885FFAR1 4743/4885FFAR4 4823/4885 |
| US-20130096315-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | KIF5B, KIF2C, PLK1 | MAOB 2959/4885FFAR1 4727/4885FFAR4 4821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.