SCHEMBL13645310

SCHEMBL13645310

C=C/C(=C\C(F)=C(C)C)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL3868358 0.75 LMNA (0.43) ALDH1A1LMNA
Acetic Acid SCHEMBL3868351 0.75 LMNA (0.43) ALDH1A1LMNA
SCHEMBL1661967 0.71 LMNA (0.50) ALDH1A1LMNA
SCHEMBL316986 0.71 LMNA (0.50) ALDH1A1LMNA
SCHEMBL345324 0.71 LMNA (0.50) ALDH1A1LMNA
SCHEMBL14104678 0.69 ALDH1A1 (0.33) ALDH1A1
SCHEMBL28414100 0.69 LMNA (0.40) ALDH1A1LMNA
SCHEMBL20822026 0.69 ALDH1A1 (0.33) ALDH1A1
SCHEMBL26580 0.68
SCHEMBL5327629 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014113485-A1 LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS INTERMUNE, INC. (US) 2014-07-24 WO disclosed
EP-2108641-A1 New substituted spiro[cycloalkyl-1,3'-indo]-2'(1'H)-one derivatives and their use as p38 mitogen-activated kinase inhibitors Laboratorios Almirall, S.A. (ES) 2009-10-14 EP disclosed