Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL3868351 | 1.00 | LMNA (0.43) | LMNAALDH1A1FFAR3LCKFYN | |
| SCHEMBL316986 | 0.92 | LMNA (0.50) | LMNAALDH1A1ALOX15HSD17B10KDM4E | |
| SCHEMBL345324 | 0.92 | LMNA (0.50) | LMNAALDH1A1ALOX15HSD17B10KDM4E | |
| SCHEMBL1661967 | 0.92 | LMNA (0.50) | LMNAALDH1A1ALOX15HSD17B10KDM4E | |
| Vinyl Chloride SCHEMBL6537138 | 0.85 | LMNA (0.43) | LMNAALOX15HSD17B10KDM4ETSHR | |
| SCHEMBL13645310 | 0.75 | ALDH1A1 (0.36) | LMNAALDH1A1 | |
| Acrylic Acid SCHEMBL9061405 | 0.74 | LMNA (0.77) | LMNAALDH1A1FFAR3LCKFYN | |
| Acrylic Acid SCHEMBL475312 | 0.74 | — | — | |
| Acrylic Acid SCHEMBL1950662 | 0.74 | LMNA (0.77) | LMNAALDH1A1FFAR3LCKFYN | |
| Acrylic Acid SCHEMBL10801174 | 0.74 | LMNA (0.77) | LMNAALDH1A1FFAR3LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139747-B2 | Image forming method | FUJIFILM CORPORATION (JP) | 2015-09-22 | — | — | US | disclosed |
| US-8721035-B2 | Image forming method | FUJIFILM CORPORATION (JP) | 2014-05-13 | — | — | US | disclosed |
| US-8556400-B2 | Inkjet recording ink | SEIKO EPSON CORPORATION (JP) | 2013-10-15 | — | — | US | disclosed |
| US-20130222501-A1 | IMAGE FORMING METHOD | FUJIFILM CORPORATION (JP) | 2013-08-29 | — | — | US | disclosed |
| US-20130222467-A1 | IMAGE FORMING METHOD | FUJIFILM CORPORATION (JP) | 2013-08-29 | — | — | US | disclosed |
| EP-1783182-B1 | INKJET RECORDING INK | SEIKO EPSON CORP (JP) | 2009-12-23 | — | — | EP | disclosed |
| EP-2123722-A1 | Ink jet recording ink | SEIKO EPSON CORPORATION (JP) | 2009-11-25 | — | — | EP | disclosed |
| US-20070263054-A1 | Inkjet Recording Ink | SEIKO EPSON CORPORATION (JP) | 2007-11-15 | — | — | US | disclosed |
| EP-1783182-A1 | INKJET RECORDING INK | SEIKO EPSON CORPORATION (JP) | 2007-05-09 | — | — | EP | disclosed |