Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16543643 | 0.69 | PTPN1 (0.34) | PTPN1 | |
| SCHEMBL21094232 | 0.66 | SPR (0.34) | — | |
| SCHEMBL14373129 | 0.65 | TPMT (0.43) | — | |
| SCHEMBL25012718 | 0.64 | PTPN1 (0.32) | PTPN1 | |
| SCHEMBL23067733 | 0.64 | LMNA (0.32) | PTPN1 | |
| SCHEMBL6858231 | 0.63 | PTPN1 (0.55) | PTPN1 | |
| SCHEMBL15263886 | 0.62 | CES2 (0.43) | — | |
| SCHEMBL14224625 | 0.62 | PTPN1 (0.30) | PTPN1 | |
| SCHEMBL24628977 | 0.61 | CTSK (0.33) | — | |
| SCHEMBL2531786 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2108641-A1 | New substituted spiro[cycloalkyl-1,3'-indo]-2'(1'H)-one derivatives and their use as p38 mitogen-activated kinase inhibitors | Laboratorios Almirall, S.A. (ES) | 2009-10-14 | — | — | EP | disclosed |