Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | IDO1 | P14902 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | AANAT | Q16613 | 1/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20648028 | 0.88 | MTNR1A (0.69) | MTNR1AMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL13645780 | 0.84 | TRPV1 (0.71) | MEN1KMT2ALMNACYP1A2BLM | |
| SCHEMBL1726381 | 0.83 | HTR2A (0.71) | MTNR1AMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL22411429 | 0.83 | HTR2A (0.71) | MTNR1AMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL14907395 | 0.83 | HTR2A (0.71) | MTNR1AMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL7022564 | 0.83 | HTR2A (0.71) | MTNR1AMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL1727120 | 0.83 | HTR2A (0.71) | MTNR1AMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL1726285 | 0.83 | HTR2A (0.71) | MTNR1AMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL1725374 | 0.83 | HTR2A (0.71) | MTNR1AMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL1724670 | 0.83 | HTR2A (0.71) | MTNR1AMEN1KMT2ALMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264496-A1 | Compounds, Compositions and Methods for Making the Same | SIGNUM BIOSCIENCES, INC. | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264496-A1 | Compounds, Compositions and Methods for Making the Same | PPP2CA, PPP4C, PPP6C | MTNR1A 1889/4885MEN1 3072/4885KMT2A 121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.