SCHEMBL2476409

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2478129	0.95	HDAC1 (0.50)	HDAC1HDAC6GAAMEN1KMT2A
	SCHEMBL3837721	0.92	HDAC1 (0.42)	HDAC1HDAC6GAAMEN1KMT2A
	SCHEMBL8000611	0.91	GAA (0.42)	HDAC1HDAC6GAAMEN1KMT2A
	SCHEMBL3229485	0.88	GAA (0.41)	HDAC1GAAKMT2AALDH1A1LMNA
	SCHEMBL3227878	0.88	GAA (0.42)	HDAC1GAAKMT2AALDH1A1LMNA
	SCHEMBL4229640	0.84	PDCD1 (0.39)	HDAC1HDAC6GAAKMT2AHTR5A
	SCHEMBL3832767	0.84	HDAC1 (0.54)	HDAC1HDAC6HDAC3HDAC2NCOR2
	SCHEMBL3834422	0.84	HDAC1 (0.54)	HDAC1HDAC6GAAHDAC3HDAC2
	SCHEMBL12051557	0.84	KDM4E (0.46)	HDAC1HDAC6MEN1KMT2AKDM1A
	SCHEMBL2476986	0.84	KDM4E (0.48)	GAAMEN1KMT2AKDM1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.