SCHEMBL2478129

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2476409	0.95	HDAC1 (0.43)	HDAC1HDAC6GAAHDAC3HDAC2
	SCHEMBL3837721	0.89	HDAC1 (0.42)	HDAC1HDAC6GAAHDAC3HDAC2
	SCHEMBL13646294	0.87	HDAC1 (0.51)	HDAC1HDAC6GAAHDAC3HDAC2
	SCHEMBL8000611	0.86	GAA (0.42)	HDAC1HDAC6GAAHDAC3HDAC2
	SCHEMBL2476986	0.86	KDM4E (0.48)	GAAKDM1AKDM4EMEN1KMT2A
	SCHEMBL3834376	0.85	GAA (0.54)	HDAC1HDAC6GAAHDAC3HDAC2
	SCHEMBL3229485	0.83	GAA (0.41)	HDAC1GAAKMT2AMLNRALDH1A1
	SCHEMBL12051557	0.83	KDM4E (0.46)	HDAC1HDAC6KDM1AKDM4EMEN1
	SCHEMBL2477923	0.83	HDAC1 (0.54)	HDAC1HDAC6HDAC3HDAC2HDAC8
	SCHEMBL3834424	0.83	HDAC1 (0.54)	HDAC1HDAC6HDAC3HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.