Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.68 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13721 | 0.89 | MTNR1A (0.53) | MTNR1AMTNR1BALDH1A1KDM4EHPGD | |
| SCHEMBL17354487 | 0.86 | MTNR1A (0.61) | MTNR1AMTNR1BALDH1A1KDM4EHPGD | |
| SCHEMBL14850269 | 0.82 | MTNR1A (0.57) | MTNR1AMTNR1BALDH1A1KDM4EHPGD | |
| SCHEMBL13643 | 0.82 | ALDH1A1 (0.54) | MTNR1AMTNR1BALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10748359 | 0.81 | MAPT (0.72) | ALDH1A1KDM4ELMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL6195294 | 0.81 | MTNR1A (1.00) | MTNR1AMTNR1BALDH1A1KDM4EHPGD | |
| SCHEMBL6838359 | 0.80 | KMT2A (0.68) | ALDH1A1KDM4ELMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL11546122 | 0.79 | LMNA (0.75) | ALDH1A1KDM4EHPGDLMNASMN1; SMN2 | |
| SCHEMBL18554186 | 0.79 | KMT2A (0.62) | ALDH1A1KDM4ELMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL14850267 | 0.79 | RAB9A (0.47) | MTNR1AMTNR1BALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011047323-A2 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2011-04-21 | — | — | WO | disclosed |