Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.60 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4940830 | 0.82 | KMT2A (0.63) | ALDH1A1MAPTSMN1; SMN2CYP1A1CYP1B1 | |
| SCHEMBL4941971 | 0.82 | ALDH1A1 (0.77) | ALDH1A1MAPTSMN1; SMN2CYP1A1CYP1B1 | |
| SCHEMBL13650898 | 0.80 | MEN1 (0.69) | ALDH1A1MAPTSMN1; SMN2CYP1A1CYP1B1 | |
| Bromide SCHEMBL22749628 | 0.79 | CYP1A1 (0.69) | ALDH1A1MAPTSMN1; SMN2CYP1A1CYP1B1 | |
| SCHEMBL22761628 | 0.79 | MEN1 (0.64) | ALDH1A1MAPTSMN1; SMN2CYP1A1CYP1B1 | |
| SCHEMBL14113975 | 0.78 | SMN1; SMN2 (0.74) | ALDH1A1MAPTSMN1; SMN2CYP1A1CYP1B1 | |
| Bromide SCHEMBL22749448 | 0.78 | CYP1A1 (0.65) | ALDH1A1MAPTSMN1; SMN2CYP1A1CYP1B1 | |
| Bromide SCHEMBL22749627 | 0.78 | MEN1 (0.66) | ALDH1A1MAPTSMN1; SMN2CYP1A1CYP1B1 | |
| Bromide SCHEMBL22749447 | 0.77 | MEN1 (0.61) | ALDH1A1MAPTSMN1; SMN2CYP1A1CYP1B1 | |
| SCHEMBL4942836 | 0.75 | ALDH1A1 (0.77) | ALDH1A1MAPTSMN1; SMN2CYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601846-B2 | Compounds having activity as inhibitors of apoptosis | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-10-13 | — | — | US | disclosed |