Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9212223 | 0.78 | LRRK2 (0.46) | LRRK2KDM4EGPR3KDM1AALDH1A1 | |
| SCHEMBL28265607 | 0.77 | ERN1 (0.58) | ERN1LRRK2KDM4EGPR3GAA | |
| Hydrochloric Acid SCHEMBL10732475 | 0.76 | LRRK2 (0.45) | LRRK2KDM4EGPR3KDM1AGAA | |
| SCHEMBL18998176 | 0.76 | ALDH1A1 (0.48) | LRRK2KDM4EKDM1AALDH1A1HPGD | |
| SCHEMBL12156904 | 0.75 | LRRK2 (0.72) | LRRK2ALDH1A1HSD17B10RAF1MAP2K1 | |
| SCHEMBL5540567 | 0.75 | ERN1 (0.55) | ERN1KDM4EGPR3GAAALDH1A1 | |
| SCHEMBL25044199 | 0.74 | IDO1 (0.44) | ERN1LRRK2KDM4EGPR3KDM1A | |
| SCHEMBL2927980 | 0.74 | ERN1 (0.58) | ERN1KDM4EGPR3GAAALDH1A1 | |
| SCHEMBL18655356 | 0.74 | LRRK2 (0.47) | LRRK2KDM4EGPR3KDM1AGAA | |
| SCHEMBL9602762 | 0.71 | KMT2A (0.49) | LRRK2KDM4EGAAALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009125809-A1 | PIPERIDINE DERIVATIVES | 第一三共株式会社 (JP) | 2009-10-15 | — | — | WO | disclosed |