Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 5/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GPR3 | P46089 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18655366 | 0.86 | HDAC3 (0.40) | LRRK2KDM1ATLR7KDM4EADORA3 | |
| SCHEMBL18655361 | 0.86 | MAPT (0.39) | LRRK2KDM1ATLR7KDM4EGPR3 | |
| SCHEMBL18655368 | 0.82 | POLB (0.48) | KDM4ELMNAMEN1ALDH1A1GLA | |
| SCHEMBL5410460 | 0.80 | KDM1A (0.66) | KDM1AKDM4EATMADORA3NUDT1 | |
| SCHEMBL18655365 | 0.78 | MAOA (0.50) | KDM1AKDM4EATMNUDT1LMNA | |
| Iodide SCHEMBL17187186 | 0.78 | KDM1A (0.63) | KDM1AKDM4EATMADORA3NUDT1 | |
| SCHEMBL18650758 | 0.74 | ACHE (0.61) | TLR7KDM4EGPR3ADORA3LMNA | |
| SCHEMBL9212223 | 0.74 | LRRK2 (0.46) | LRRK2KDM1AKDM4EGPR3ATM | |
| SCHEMBL13652174 | 0.74 | ERN1 (0.50) | LRRK2KDM1AKDM4EGPR3ATM | |
| SCHEMBL18650740 | 0.74 | MAOA (0.61) | TLR7KDM4EGPR3ADORA3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170081351-A1 | Design, Synthesis, and Biological Activity of Platinum-benz[c]acridine Hybrid Agents and Methods Associated Therewith | WAKE FOREST UNIVERSITY | 2017-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170081351-A1 | Design, Synthesis, and Biological Activity of Platinum-benz[c]acridine Hybrid Agents and Methods Associated Therewith | ACR, TP53, MCL1 | LRRK2 1199/4885KDM1A 3582/4885TLR7 1979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.