Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13652835 | 0.90 | ACSS2 (0.35) | SMN1; SMN2CNR1CNR2ACSS2ACLY | |
| SCHEMBL2612597 | 0.90 | SHBG (0.36) | ESR1CYP3A4SHBGALDH1A1 | |
| SCHEMBL13652836 | 0.88 | CNR1 (0.36) | SMN1; SMN2ESR1CYP3A4CNR1CNR2 | |
| SCHEMBL13652822 | 0.84 | ACSS2 (0.37) | SMN1; SMN2MEN1CYP3A4MAPTKMT2A | |
| SCHEMBL13652824 | 0.83 | CNR1 (0.36) | SMN1; SMN2ESR1CYP3A4CNR1CNR2 | |
| SCHEMBL13652841 | 0.81 | NPY2R (0.36) | PGR | |
| SCHEMBL13652823 | 0.81 | ESR1 (0.36) | ESR1CYP3A4CNR1CNR2SHBG | |
| SCHEMBL13652815 | 0.79 | CYP3A4 (0.34) | SMN1; SMN2ESR1CYP3A4MAPK1CNR1 | |
| SCHEMBL13652834 | 0.79 | MDH1 (0.30) | — | |
| SCHEMBL769152 | 0.79 | NPC1 (0.38) | SMN1; SMN2MEN1USP2ESR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090246416-A1 | OPTICAL FILM, METHOD OF MANUFACTURING THE SAME, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE | KONICA MINOLTA OPTO, INC. (JP) | 2009-10-01 | — | — | US | disclosed |