SCHEMBL13653145

SCHEMBL13653145

CC(=O)NCCc1nc(-c2ccccc2)c(-c2ccccc2)o1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 14/20 0.64
RXRA P19793 9/20 0.64
RXRB P28702 8/20 0.64
RXRG P48443 5/20 0.64
NR4A1 P22736 3/20 0.64
NR4A3 Q92570 3/20 0.64
KDM4E B2RXH2 2/20 0.64
LMNA P02545 2/20 0.64
ABCC4 O15439 1/20 0.64
C5 P01031 1/20 0.64
CHRM2 P08172 1/20 0.64
CYP3A4 P08684 1/20 0.64
CHRM1 P11229 1/20 0.64
DRD2 P14416 1/20 0.64
HPGD P15428 1/20 0.64
TSHR P16473 1/20 0.64
TBXA2R P21731 1/20 0.64
PTGS1 P23219 1/20 0.64
HTR2A P28223 1/20 0.64
HTR2C P28335 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31582283 0.87 NR4A2 (0.62) NR4A2RXRARXRBRXRGNR4A1
SCHEMBL11715199 0.86 NR4A2 (0.67) NR4A2RXRARXRBRXRGNR4A1
SCHEMBL12608914 0.82 RXRA (0.78) NR4A2RXRARXRBRXRGNR4A1
SCHEMBL25942922 0.81 NR4A2 (0.64) NR4A2RXRARXRBRXRGNR4A1
Oxaprozin SCHEMBL8607424 0.81 RXRA (0.91) NR4A2RXRARXRBRXRGNR4A1
Oxaprozin SCHEMBL28060624 0.81 RXRA (0.91) NR4A2RXRARXRBRXRGNR4A1
Hydrochloric Acid SCHEMBL11717435 0.80 NR4A2 (0.63) NR4A2RXRARXRBRXRGNR4A1
SCHEMBL31582641 0.79 NR4A2 (0.77) NR4A2RXRARXRBRXRGNR4A1
SCHEMBL14867495 0.79 NR4A2 (0.73) NR4A2RXRARXRBRXRGNR4A1
Oxaprozin SCHEMBL3286 0.79 RXRA (1.00) NR4A2RXRARXRBRXRGNR4A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250163006-A1 New Coolants, and Preparations Containing Same SYMRISE AG (DE) 2025-05-22 US claimed
WO-2025132323-A1 COMPOSITIONS COMPRISING A SUNSCREEN ACTIVE AGENT DSM-FIRMENICH AG (CH) 2025-06-26 WO disclosed
US-20250163006-A1 New Coolants, and Preparations Containing Same SYMRISE AG (DE) 2025-05-22 US disclosed
US-20090247488-A1 ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS CANNIZZARO CARINA 2009-10-01 US disclosed
US-7432261-B2 Anti-inflammatory phosphonate compounds GILEAD SCIENCES, INC. (US) 2008-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247488-A1 ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS PHOSPHO1, TNF, PTGES NR4A2 1050/4885RXRA 1906/4885RXRB 2036/4885
US-20250163006-A1 New Coolants, and Preparations Containing Same TTR, TAS2R5, TAS2R50 NR4A2 3460/4885RXRA 1599/4885RXRB 2626/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.