Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP51A1 | Q16850 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14080289 | 0.88 | TP53 (0.43) | CA2TP53CYP51A1CA1CA5A | |
| SCHEMBL30874461 | 0.87 | CYP51A1 (0.49) | CA2TP53CYP51A1CA1CA5A | |
| Ammonia Solution, Strong SCHEMBL28172254 | 0.86 | TP53 (0.42) | CA2TP53CYP51A1CA1CA5A | |
| SCHEMBL13449507 | 0.83 | TP53 (0.48) | CA2TP53CYP51A1CA1CA5A | |
| SCHEMBL26220277 | 0.79 | NOS3 (0.50) | CA2TP53CYP51A1TDP1KDM4E | |
| SCHEMBL15290259 | 0.79 | PTGS2 (0.44) | CA2TP53CYP51A1CA1CA5A | |
| SCHEMBL20552585 | 0.79 | CYP51A1 (0.44) | CA2TP53CYP51A1CA1CA5A | |
| SCHEMBL30906028 | 0.79 | CYP51A1 (0.44) | CA2TP53CYP51A1CA1CA5A | |
| SCHEMBL15590856 | 0.78 | CYP51A1 (0.49) | CA2TP53CYP51A1TDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL19925268 | 0.78 | NOS3 (0.52) | CA2TP53CYP51A1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250090672-A1 | CHEMOSELECTIVE THIOL-CONJUGATION WITH ALKENE OR ALKYNE-PHOSPHONAMIDATES | FORSCHUNGSVERBUND BERLIN EV (DE) | 2025-03-20 | — | — | US | disclosed |
| US-12171837-B2 | Chemoselective thiol-conjugation with alkene or alkyne-phosphonamidates | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2024-12-24 | — | — | US | disclosed |
| CN-117903297-A | Chemoselective coupling of sulfhydryl groups with alkenyl or alkynyl phosphoramides | 柏林合作研究学会 | 2024-04-19 | — | — | CN | disclosed |
| US-20230348529-A1 | CHEMOSELECTIVE THIOL-CONJUGATION WITH ALKENE OR ALKYNE-PHOSPHONAMIDATES | FORSCHUNGSVERBUND BERLIN EV (DE) | 2023-11-02 | — | — | US | disclosed |
| US-20230348529-A1 | CHEMOSELECTIVE THIOL-CONJUGATION WITH ALKENE OR ALKYNE-PHOSPHONAMIDATES | FORSCHUNGSVERBUND BERLIN EV (DE) | 2023-11-02 | — | — | US | disclosed |
| US-20230348529-A1 | CHEMOSELECTIVE THIOL-CONJUGATION WITH ALKENE OR ALKYNE-PHOSPHONAMIDATES | FORSCHUNGSVERBUND BERLIN EV (DE) | 2023-11-02 | — | — | US | disclosed |
| CN-109689112-B | Chemoselective coupling of sulfhydryl groups with alkenyl or alkynyl phosphoramides | 柏林合作研究学会 | 2023-10-13 | — | — | CN | disclosed |
| US-11746124-B2 | Chemoselective thiol-conjugation with alkene or alkyne-phosphonamidates | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2023-09-05 | — | — | US | disclosed |
| US-11746124-B2 | Chemoselective thiol-conjugation with alkene or alkyne-phosphonamidates | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2023-09-05 | — | — | US | disclosed |
| US-11746124-B2 | Chemoselective thiol-conjugation with alkene or alkyne-phosphonamidates | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2023-09-05 | — | — | US | disclosed |
| US-20120252747-A1 | MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | SILICON VALLEY BANK | 2012-10-04 | — | — | US | disclosed |
| US-20120252747-A1 | MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | SILICON VALLEY BANK | 2012-10-04 | — | — | US | disclosed |
| US-8202843-B2 | Macrocyclic compounds and methods of making and using the same | RIB-X PHARMACEUTICALS, INC. (US) | 2012-06-19 | — | — | US | disclosed |
| US-8202843-B2 | Macrocyclic compounds and methods of making and using the same | RIB-X PHARMACEUTICALS, INC. (US) | 2012-06-19 | — | — | US | disclosed |
| US-20090269555-A1 | SURFACE NANOPATTERNING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-10-29 | — | — | US | disclosed |
| US-20090269555-A1 | SURFACE NANOPATTERNING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-10-29 | — | — | US | disclosed |
| US-7524408-B2 | photoreduction of an azide, photodecarbozylation of a carboxylic acid, photodenitrogenation and Wolff rearrangement of a diazoketone, and the photoreduction of an aromatic nitrocompound; charged nanoparticle from CdS and CdSe compounds as path-directable nanoparticle; | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-04-28 | — | — | US | disclosed |
| US-7524408-B2 | photoreduction of an azide, photodecarbozylation of a carboxylic acid, photodenitrogenation and Wolff rearrangement of a diazoketone, and the photoreduction of an aromatic nitrocompound; charged nanoparticle from CdS and CdSe compounds as path-directable nanoparticle; | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-04-28 | — | — | US | disclosed |
| US-20080045585-A1 | Macrocyclic Compounds And Methods Of Making And Using The Same | BioVersys AG (CH) | 2008-02-21 | — | — | US | disclosed |
| US-20080045585-A1 | Macrocyclic Compounds And Methods Of Making And Using The Same | BioVersys AG (CH) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12171837-B2 | Chemoselective thiol-conjugation with alkene or alkyne-phosphonamidates | PFAS, PHOSPHO1, PNKP | CA2 4473/4885TP53 3347/4885CYP51A1 3379/4885 |
| US-20120252747-A1 | MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | CCNO, PTGDR, CCNE1 | CA2 2606/4885TP53 1652/4885CYP51A1 508/4885 |
| US-20230348529-A1 | CHEMOSELECTIVE THIOL-CONJUGATION WITH ALKENE OR ALKYNE-PHOSPHONAMIDATES | PFAS, PHOSPHO1, PNKP | CA2 4473/4885TP53 3347/4885CYP51A1 3379/4885 |
| US-20080045585-A1 | Macrocyclic Compounds And Methods Of Making And Using The Same | VIP, PROKR1, PGC | CA2 3768/4885TP53 2788/4885CYP51A1 608/4885 |
| US-20250090672-A1 | CHEMOSELECTIVE THIOL-CONJUGATION WITH ALKENE OR ALKYNE-PHOSPHONAMIDATES | PFAS, PHOSPHO1, PNKP | CA2 4473/4885TP53 3347/4885CYP51A1 3379/4885 |
| US-11746124-B2 | Chemoselective thiol-conjugation with alkene or alkyne-phosphonamidates | PFAS, PHOSPHO1, PNKP | CA2 4473/4885TP53 3347/4885CYP51A1 3379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.