Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13659655 | 0.93 | KDM4E (0.42) | KDM4ENPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL402705 | 0.92 | SMN1; SMN2 (0.45) | KDM4ENPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL13655038 | 0.90 | HTT (0.39) | SMN1; SMN2 | |
| SCHEMBL13655005 | 0.90 | KDM4E (0.43) | KDM4E | |
| SCHEMBL13655009 | 0.88 | KMT2A (0.49) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13655014 | 0.85 | HDAC1 (0.40) | ALDH1A1 | |
| SCHEMBL1912181 | 0.84 | SMN1; SMN2 (0.47) | KDM4ENPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL13654997 | 0.84 | KDM4E (0.42) | KDM4EALDH1A1 | |
| SCHEMBL13655028 | 0.83 | LMNA (0.44) | KDM4EALDH1A1 | |
| SCHEMBL13655035 | 0.83 | HDAC1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247506-A1 | Antibacterial agents | CHIRON CORPORATION | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247506-A1 | Antibacterial agents | MRPL21, SI, PGLS | KDM4E 4327/4885NPC1 371/4885ALDH1A1 782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.