Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13659668 | 0.94 | MAPT (0.48) | MAPTKDM4EPOLBHDAC1ANPEP | |
| SCHEMBL400720 | 0.93 | HDAC1 (0.48) | MAPTKDM4EPOLBHDAC1ANPEP | |
| SCHEMBL13655024 | 0.91 | NAMPT (0.41) | MAPTKDM4EPOLBLMNAHPGD | |
| SCHEMBL435606 | 0.90 | HDAC1 (0.47) | MAPTKDM4EPOLBHDAC1ANPEP | |
| SCHEMBL13655022 | 0.89 | KDM4E (0.38) | MAPTKDM4ELMNAHPGD | |
| SCHEMBL13655014 | 0.89 | HDAC1 (0.40) | HDAC1 | |
| SCHEMBL13655011 | 0.89 | ANPEP (0.40) | MAPTANPEPLMNAHPGD | |
| SCHEMBL13655023 | 0.86 | PTGES (0.39) | MAPTPOLB | |
| SCHEMBL1109323 | 0.85 | HDAC1 (0.51) | MAPTKDM4EPOLBHDAC1ANPEP | |
| SCHEMBL13659495 | 0.84 | ROCK2 (0.42) | MAPTKDM4EPOLBLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247506-A1 | Antibacterial agents | CHIRON CORPORATION | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247506-A1 | Antibacterial agents | MRPL21, SI, PGLS | MAPT 4619/4885KDM4E 4327/4885POLB 640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.