Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13655088 | 0.81 | RECQL (0.37) | HTR5ARECQLTSHRMAPK1HTR2A | |
| SCHEMBL13655085 | 0.76 | MAPT (0.47) | DHFR | |
| SCHEMBL13655360 | 0.68 | PTGES (0.38) | HTR5ADHFR | |
| SCHEMBL4244094 | 0.66 | DRD2 (0.45) | MAPK1HTR2AACACBDHFR | |
| Hydrochloric Acid SCHEMBL4243290 | 0.65 | HTR6 (0.47) | HTR2AACACBDHFR | |
| SCHEMBL18135576 | 0.63 | ACACB (0.60) | ACACB | |
| SCHEMBL10191871 | 0.63 | ACACB (0.46) | MAPK1ACACB | |
| SCHEMBL9469409 | 0.61 | HTR2A (0.45) | HTR2A | |
| SCHEMBL12287731 | 0.60 | ACACB (0.43) | ACACBDHFRHSP90AA1HSP90AB1 | |
| SCHEMBL15959652 | 0.59 | GRIN2B (0.49) | TSHRMAPK1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123753-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-08 | — | — | WO | disclosed |