Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 5/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13655367 | 0.73 | GRM5 (0.36) | GRM5MEN1KMT2AABL1KCNH2 | |
| SCHEMBL13655361 | 0.73 | MAPT (0.43) | GRM5MEN1KMT2AFFAR1 | |
| SCHEMBL13655085 | 0.72 | MAPT (0.47) | GRM5MEN1KMT2ADHFR | |
| SCHEMBL17887717 | 0.70 | NOS1 (0.41) | MEN1KMT2A | |
| SCHEMBL13655204 | 0.70 | NOS1 (0.41) | MEN1KMT2A | |
| SCHEMBL2774016 | 0.69 | FFAR1 (0.60) | PTGESGRM5L3MBTL1MEN1KMT2A | |
| SCHEMBL13655366 | 0.68 | HTR5A (0.36) | HTR5ADHFR | |
| SCHEMBL28353226 | 0.68 | GRM5 (0.49) | PTGESGRM5L3MBTL1MEN1KMT2A | |
| SCHEMBL29997548 | 0.68 | GRM5 (0.49) | PTGESGRM5L3MBTL1MEN1KMT2A | |
| SCHEMBL4214499 | 0.67 | CA1 (0.60) | GRM5L3MBTL1MEN1KMT2AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123753-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-08 | — | — | WO | disclosed |