SCHEMBL2347336

SCHEMBL2347336

O=C(NCCCN1CCOCC1)NCCCN1CCOCC1

nearest known ligand 0.70

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.70
HPGD P15428 1/20 0.68
DUSP3 P51452 1/20 0.68
LMNA P02545 2/20 0.68
KDM4E B2RXH2 2/20 0.68
EPHX1 P07099 1/20 0.68
TSHR P16473 2/20 0.64
EPHX2 P34913 1/20 0.64
ALDH1A1 P00352 3/20 0.64
MAPK1 P28482 1/20 0.64
HIF1A Q16665 1/20 0.64
SMN1; SMN2 Q16637 2/20 0.62
MAPT P10636 1/20 0.62
RAB9A P51151 1/20 0.62
POLB P06746 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14365891 0.90 GAA (0.62) GAAHPGDDUSP3LMNAKDM4E
SCHEMBL1514666 0.89 GAA (0.57) GAAHPGDDUSP3LMNAKDM4E
SCHEMBL13655375 0.89 LMNA (0.84) GAAHPGDDUSP3LMNAKDM4E
SCHEMBL3897267 0.88 SMN1; SMN2 (0.60) GAALMNAKDM4EEPHX1TSHR
SCHEMBL2339550 0.87 ALDH1A1 (0.59) GAAHPGDDUSP3LMNAKDM4E
SCHEMBL76649 0.87 GAA (0.68) GAAHPGDDUSP3LMNAKDM4E
SCHEMBL1768797 0.86 GAA (0.58) GAAHPGDDUSP3LMNAKDM4E
SCHEMBL1768801 0.86 GAA (0.58) GAAHPGDDUSP3LMNAKDM4E
SCHEMBL11742767 0.85 LMNA (0.69) GAAHPGDDUSP3LMNAKDM4E
SCHEMBL8762651 0.85 GAA (0.66) GAAHPGDDUSP3LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9657129-B2 Cyclic amine compound and process for producing polyurethane resin by using it TOSOH CORPORATION (JP) 2017-05-23 US claimed
EP-2657237-B1 CYCLIC AMINE COMPOUND, AND PROCESS FOR PRODUCING POLYURETHANE RESIN USING SAME TOSOH CORP (JP) 2015-05-20 EP claimed
US-20130289232-A1 NOVEL CYCLIC AMINE COMPOUND AND PROCESS FOR PRODUCING POLYURETHANE RESIN BY USING IT TOSOH CORPORATION (JP) 2013-10-31 US claimed
EP-2657237-A1 NOVEL CYCLIC AMINE COMPOUND, AND PROCESS FOR PRODUCING POLYURETHANE RESIN USING SAME Tosoh Corporation (JP) 2013-10-30 EP claimed
EP-1443065-B1 Low acid organometallic catalyst for the production of flexible, semi-flexible and rigid polyurethane foams AIR PROD & CHEM (US) 2006-09-13 EP claimed
EP-1534766-A1 PROCESS FOR PREPARING POLYURETHANE FOAM GENERAL ELECTRIC COMPANY (US) 2005-06-01 EP claimed
US-6825238-B2 BISMUTH CARBOXYLATE OR BISMUTH SULFONATE HAVING LESS THAN 34% FREE ACID AS THE ORGANOMETALLIC CATALYST AIR PRODUCTS AND CHEMICALS, INC. 2004-11-30 US claimed
US-6818675-B2 USING REACTION PRODUCT OF TERTIARY AMINE AND ACID AS POLYMERIZATION CATALYST GENERAL ELECTRIC COMPANY 2004-11-16 US claimed
EP-0877042-B1 Reactive catalyst compositions for improving water blown polyurethane foam performance AIR PROD & CHEM (US) 2004-09-22 EP claimed
EP-1443065-A1 Low acid organometallic catalyst for the production of flexible, semi-flexible and rigid polyurethane foams AIR PRODUCTS AND CHEMICALS, INC. (US) 2004-08-04 EP claimed
US-20040147626-A1 LOW ACID ORGANOMETALLIC CATALYST FOR THE PRODUCTION OF FLEXIBLE, SEMI-FLEXIBLE AND RIGID POLYURETHANE FOAMS EVONIK DEGUSSA GMBH (DE) 2004-07-29 US claimed
WO-2004013201-A1 PROCESS FOR PREPARING POLYURETHANE FOAM GENERAL ELECTRIC COMPANY (US) 2004-02-12 WO claimed
US-20040029986-A1 Process for preparing polyurethane foam CROMPTON CORPORATION 2004-02-12 US claimed
EP-0877042-A1 Reactive catalyst compositions for improving water blown polyurethane foam performance AIR PRODUCTS AND CHEMICALS, INC. (US) 1998-11-11 EP claimed
EP-2787016-B1 Fast demold/extended cream time polyurethane formulations EVONIK DEGUSSA GMBH (DE) 2019-01-30 EP disclosed
EP-1534766-B2 PROCESS FOR PREPARING POLYURETHANE FOAM MOMENTIVE PERFORMANCE MAT INC (US) 2018-01-17 EP disclosed
CN-104854265-B copper plating bath composition 德国艾托特克公司 2017-08-08 CN disclosed
EP-0877017-A1 Aminomethyl pyrrolidine urea compositions for the production of polyurethanes AIR PRODUCTS AND CHEMICALS, INC. (US) 1998-11-11 EP disclosed
US-5824711-A CATALYTIC REACTION OF POLYISOCYANATE AND POLYOL IN THE PRESENCE OF BLOWING AGENT FOR FORMING POLYURETHANES AIR PRODUCTS AND CHEMICALS, INC. (US) 1998-10-20 US disclosed
US-5756557-A CATALYSTS IN THE PREPARATION OF POLYURETHANE FOAMS AIR PRODUCTS AND CHEMICALS, INC. (US) 1998-05-26 US disclosed