Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.32 |
| ▸ | CDK2 | P24941 | 3/20 | 0.32 |
| ▸ | GSK3B | P49841 | 3/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.31 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6209835 | 0.80 | POLB (0.43) | RAB9ANPC1GSK3BKMT2AALDH1A1 | |
| SCHEMBL6209840 | 0.80 | POLB (0.43) | RAB9ANPC1GSK3BKMT2AALDH1A1 | |
| SCHEMBL14860713 | 0.79 | LOX (0.47) | LOXLOXL2ACACBGSK3BITGA4 | |
| SCHEMBL13655387 | 0.75 | MEN1 (0.46) | LOXLOXL2ACACBKMT2APOLB | |
| SCHEMBL6232713 | 0.74 | NPC1 (0.55) | RAB9ANPC1GSK3BKMT2AALDH1A1 | |
| SCHEMBL6237990 | 0.73 | ALDH1A1 (0.44) | RAB9ANPC1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL6209680 | 0.73 | CNR1 (0.44) | RAB9ANPC1KMT2ACYP3A4 | |
| SCHEMBL4058914 | 0.72 | POLB (0.34) | RAB9ANPC1KMT2AALDH1A1POLB | |
| SCHEMBL6210731 | 0.71 | LMNA (0.44) | KMT2ATSHRALDH1A1POLBMEN1 | |
| SCHEMBL6210717 | 0.71 | LMNA (0.44) | KMT2ATSHRALDH1A1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1450750-B1 | USE OF 2-AMINO-4-PYRIDYLMETHYL-THIAZOLINE DERIVATIVES AS INHIBITORS OF INDUCIBLE NO-SYNTHASE | AVENTIS PHARMA SA (FR) | 2009-10-21 | — | — | EP | disclosed |