Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | LOX | P28300 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13655383 | 0.75 | LOX (0.42) | MEN1KMT2ALOXLOXL2MAPT | |
| SCHEMBL13975843 | 0.73 | LOX (0.53) | LOXLOXL2SMN1; SMN2POLB | |
| SCHEMBL14860713 | 0.70 | LOX (0.47) | LOXLOXL2ACACB | |
| SCHEMBL13655319 | 0.67 | LOXL2 (0.60) | LOXLOXL2ACACB | |
| SCHEMBL12093674 | 0.66 | LOXL2 (0.62) | LOXLOXL2SMN1; SMN2ACACBPOLB | |
| SCHEMBL21227109 | 0.66 | LOX (0.54) | LOXLOXL2ALOX12ACACB | |
| SCHEMBL19492384 | 0.65 | LOX (0.57) | LOXLOXL2 | |
| SCHEMBL12093688 | 0.65 | LOXL2 (0.61) | LOXLOXL2ACACB | |
| SCHEMBL21591538 | 0.65 | GSK3A (0.50) | LOXLOXL2POLB | |
| SCHEMBL2140980 | 0.64 | LOX (0.46) | LOXLOXL2ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1450750-B1 | USE OF 2-AMINO-4-PYRIDYLMETHYL-THIAZOLINE DERIVATIVES AS INHIBITORS OF INDUCIBLE NO-SYNTHASE | AVENTIS PHARMA SA (FR) | 2009-10-21 | — | — | EP | disclosed |