Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | STS | P08842 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
| ▸ | TBK1 | Q9UHD2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11563475 | 0.84 | ALOX15 (0.51) | ALOX15STSMAPTHTTADCY1 | |
| SCHEMBL23334899 | 0.80 | TNKS (0.49) | MAPTTNKSPARP1TNKS2HDAC6 | |
| SCHEMBL11554487 | 0.79 | STS (0.46) | ALOX15STSMAPTHTTADCY1 | |
| SCHEMBL23334588 | 0.79 | MAPT (0.73) | ALOX15STSMAPTHTTADCY1 | |
| SCHEMBL13310593 | 0.78 | TNKS (0.50) | MAPTHTTADCY1TNKSPARP1 | |
| SCHEMBL7574697 | 0.78 | ALOX15 (0.66) | ALOX15STSMAPTHTTADCY1 | |
| SCHEMBL12357035 | 0.77 | LMNA (0.39) | ALOX15STSMAPTHTTTBK1 | |
| SCHEMBL11554491 | 0.76 | ALOX15 (0.46) | ALOX15STSMAPTHTTADCY1 | |
| SCHEMBL5557517 | 0.75 | ALDH1A1 (0.63) | MAPTHTTTNKSPARP1TNKS2 | |
| SCHEMBL12867892 | 0.75 | ALOX15 (0.57) | ALOX15STSMAPTHTTTNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021085372-A1 | RESIN COMPOSITION, COMPOUND (Z), OPTICAL FILTER, AND USE THEREOF | JSR株式会社 | 2021-05-06 | — | — | WO | disclosed |
| US-7605176-B2 | β-ketoamide compounds with MCH antagonistic activity | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-10-20 | — | — | US | disclosed |