SCHEMBL13657385

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12736229	0.90	TP53 (0.58)	MGLLSMN1; SMN2NPC1RAB9ATP53
	SCHEMBL15986678	0.89	SIGMAR1 (0.59)	PARP1SIGMAR1MGLLSMN1; SMN2NPC1
	SCHEMBL1696388	0.86	NPC1 (0.63)	MGLLSMN1; SMN2NPC1RAB9ATP53
	SCHEMBL13650892	0.85	SIGMAR1 (0.55)	PARP1SIGMAR1CNR2SMN1; SMN2NPC1
	SCHEMBL13657383	0.84	SMN1; SMN2 (0.56)	PARP1MGLLSMN1; SMN2NPC1RAB9A
	SCHEMBL1763270	0.84	SIGMAR1 (0.61)	PARP1SIGMAR1SMN1; SMN2TP53GABRD
	SCHEMBL10272898	0.83	RAB9A (0.65)	PARP1MGLLSMN1; SMN2NPC1RAB9A
	SCHEMBL12012931	0.83	POLB (0.50)	PARP1MGLLSMN1; SMN2NPC1RAB9A
	SCHEMBL20245216	0.82	SIGMAR1 (0.58)	SIGMAR1MGLLCNR2SMN1; SMN2GABRD
	SCHEMBL8358286	0.82	SIGMAR1 (0.76)	SIGMAR1TP53GABRDGABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.