Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20109868 | 0.90 | CYP2D6 (0.40) | BCHEF10CYP2D6THRBHSD17B10 | |
| SCHEMBL12021728 | 0.90 | CYP2D6 (0.40) | BCHEF10CYP2D6THRBHSD17B10 | |
| SCHEMBL13553167 | 0.90 | OGA (0.40) | BCHECYP2D6THRBHSD17B10NR3C1 | |
| SCHEMBL10028972 | 0.90 | OGA (0.40) | BCHECYP2D6THRBHSD17B10NR3C1 | |
| SCHEMBL27108843 | 0.90 | OGA (0.40) | BCHECYP2D6THRBHSD17B10NR3C1 | |
| SCHEMBL12378498 | 0.90 | OGA (0.40) | BCHECYP2D6THRBHSD17B10NR3C1 | |
| SCHEMBL15982003 | 0.90 | OGA (0.40) | BCHECYP2D6THRBHSD17B10NR3C1 | |
| SCHEMBL12308552 | 0.90 | OGA (0.40) | BCHECYP2D6THRBHSD17B10NR3C1 | |
| SCHEMBL14478874 | 0.90 | OGA (0.40) | BCHECYP2D6THRBHSD17B10NR3C1 | |
| SCHEMBL13658766 | 0.88 | LGALS8 (0.40) | BCHEF10CYP2D6THRBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208916-A1 | AMYLOID TARGETING AGENTS AND METHODS OF USING THE SAME | Amydis, Inc. | 2024-06-27 | — | — | US | disclosed |
| US-11718596-B2 | Amyloid targeting agents and methods of using the same | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-08-08 | — | — | US | disclosed |
| US-10005745-B2 | Amyloid targeting agents and methods of using the same | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-06-26 | — | — | US | disclosed |
| US-20160326126-A1 | AMYLOID TARGETING AGENTS AND METHODS OF USING THE SAME | Amydis, Inc. | 2016-11-10 | — | — | US | disclosed |
| US-20090264639-A1 | Polysaccharide derivative and separating agent for optical isomer containing the same | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718596-B2 | Amyloid targeting agents and methods of using the same | APP, CRYAA, APBA1 | BCHE 66/4885F10 1929/4885CYP2D6 4354/4885 |
| US-20240208916-A1 | AMYLOID TARGETING AGENTS AND METHODS OF USING THE SAME | APP, CRYAA, APBA1 | BCHE 66/4885F10 1929/4885CYP2D6 4354/4885 |
| US-20160326126-A1 | AMYLOID TARGETING AGENTS AND METHODS OF USING THE SAME | APP, APBA1, CRYAA | BCHE 77/4885F10 1985/4885CYP2D6 4377/4885 |
| US-20090264639-A1 | Polysaccharide derivative and separating agent for optical isomer containing the same | FUT5, FUT6, DDOST | BCHE 1709/4885F10 1722/4885CYP2D6 4004/4885 |
| US-10005745-B2 | Amyloid targeting agents and methods of using the same | APP, APBA1, CRYAA | BCHE 77/4885F10 1985/4885CYP2D6 4377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.