Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.59 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.56 |
| ▸ | FUT8 | Q9BYC5 | 2/20 | 0.56 |
| ▸ | CHAT | P28329 | 4/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | APEX1 | P27695 | 2/20 | 0.54 |
| ▸ | P2RY12 | Q9H244 | 7/20 | 0.54 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.53 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.53 |
| ▸ | P2RY4 | P51582 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13320765 | 0.81 | GNG2 (0.61) | P2RY1P2RY12P2RY4CYP2C9ALOX15 | |
| SCHEMBL14437907 | 0.81 | HPGDS (0.61) | HPGDSP2RY1FUT8CHATUSP2 | |
| SCHEMBL11885193 | 0.79 | HPGDS (0.59) | HPGDSP2RY1FUT8CHATUSP2 | |
| SCHEMBL13320766 | 0.79 | GNG2 (0.62) | P2RY1P2RY12P2RY4CYP3A4CYP2C9 | |
| SCHEMBL13320767 | 0.78 | GNG2 (0.61) | P2RY1P2RY12P2RY4CYP2C9ALOX15 | |
| SCHEMBL13320764 | 0.74 | GNG2 (0.48) | P2RY1P2RY12P2RY4CYP3A4CYP2C9 | |
| Cibacron Blue SCHEMBL4350042 | 0.74 | HPGDS (1.00) | HPGDSP2RY1FUT8CHATUSP2 | |
| Cibacron Blue SCHEMBL29558558 | 0.74 | HPGDS (1.00) | HPGDSP2RY1FUT8CHATUSP2 | |
| Cibacron Blue SCHEMBL30286286 | 0.74 | HPGDS (1.00) | HPGDSP2RY1FUT8CHATUSP2 | |
| Cibacron Blue SCHEMBL29373073 | 0.74 | HPGDS (1.00) | HPGDSP2RY1FUT8CHATUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090263784-A1 | THREE-DIMENSIONAL STRUCTURE OF PROSTAGLANDIN D SYNTHASE AND UTILIZATION THEREOF | URADE YOSHIHIRO | 2009-10-22 | — | — | US | disclosed |
| US-7547532-B2 | Three-dimensional structure of prostaglandin D synthase and utilization thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2009-06-16 | — | — | US | disclosed |